Thursday, 28 August 2008

New Prostate Cancer Test Is Ready For Commercialization Following Successful Completion Of Final Clinical Trials

�Health Discovery Corporation ("HDC") (OTCBB: HDVY) announced that HDC's new gene-based molecular diagnostic test for prostate cancer has now successfully completed it's Phase III double-blind clinical trial and is forthwith ready for commercialization to be used by physicians on their patients at risk of having prostate cancer. The new prostate cancer quiz will be performed at Clarient's Clinical Laboratory in Aliso Viejo, CA. HDC will receive 30% royal family on each test performed.


Results from Phase I, Phase II and Phase III double-blinded clinical validation studies now completed with prostate tissues obtained from multiple sites, including those tested in collaboration with MD Anderson Cancer Center, demonstrated a very heights success pace for identifying the presence of Grade 3 or higher prostate gland cancer cells (clinically significant cancer), as well as, normal and BPH (benign prostatic hyperplasia) cells. To date, 322 prostate tissues have been tested. The combined results of the recently realised double-blinded clinical validation studies demonstrated that the young gene-based molecular diagnostic test for prostate cancer achieved a Sensitivity of 90% for right identifying the presence of Grade 3 or higher prostate cancer cells, and a Specificity of 97% for correctly identifying non-cancer cells (normal and BPH), representing an overall try accuracy of 93%.


"We are selfsame pleased with the net results of the double blind clinical trial and are excited to have our first tax income producing molecular diagnostic test ready for commercialization," declared Stephen D. Barnhill, M.D., Chairman and CEO of Health Discovery Corporation. "The successful ontogeny, validation and commercialization of this new molecular symptomatic test for prostate malignant neoplastic disease proves that HDC, by combining our patented SVM and SVM-RFE technology and our expert Scientific Team, has the ability to produce new molecular symptomatic and portent tests which are the future of personalized medicine. Our patent protected discovery method allows us to develop molecular diagnostic and prognostic tests that are free of outside intellectual property rights and thereby allows HDC to fully patent protect our molecular diagnostic factor signatures. Using the same expertise of our Scientific Team and the HDC patented engineering, we are currently development additional unexampled molecular symptomatic tests in a variety of other cancers some of which we hope will be commercially uncommitted in Q4 of 2008."


Dr. Barnhill continued "We are proud of to take in HDC's new gene-based prostate cancer quiz enter the market like similar molecular diagnostic tests based on unique cistron expression profiles such as OncotypeDX from Genomic Health, Inc. (NasdaqGM:GHDX) and MammaPrint from Agendia."


In the United States alone thither are over 1 1000000 prostate genus Cancer tissue biopsy procedures performed annually. Approximately 25% of these tissue biopsies ar reported "cocksure" indicating the presence of prostate crab. The other 75% of prostate cancer tissue biopsies are reported as "negative" for the presence of cancer. However, one-third of the workforce with initial prostate cancer tissue biopsies that are reported as "negative" for prostate crab (roughly 25% of men at risk of having prostate crab) actually do have prostate cancer that was lost by the first biopsy (False Negative). These men actually have prostate cancer that was missed by the initial tissue biopsy for a variety of reasons. Health Discovery Corporation's prostate cancer molecular diagnostic test is a genomics based test that should be performed on the 75% of men (about 600,000 men each year in the US unequaled) with initial biopsies reported as negative to attend physicians in identifying those men world Health Organization could get prostate cancer that was missed by the low biopsy.


"The excellent results seen in Phase I, Phase II, and Phase III double-blinded clinical trials validate the scientific truth and robustness of the HDC gene-based molecular symptomatic test for prostate cancer," stated Dr. Herbert Fritsche, Professor of Laboratory Medicine and Chief of the Clinical Chemistry Section at The University of Texas, M.D. Anderson Cancer Center in Houston, Texas. "Physicians that ar diagnosing and treating prostate gland cancer patients will be greatly assisted by the additional information that this new prostate cancer quiz will add together to their decision devising process."


In a Press Release issued yesterday, Ron Andrews, CEO of Clarient stated "We are selfsame impressed with the results from these validation studies, and I applaud the development teams from both Clarient and HDC for their persevering efforts in bringing this new test through the validation phase angle significantly ahead of schedule. The early results from these studies confirm our belief that this potent genomics-based test may leave physicians with useful information to assure that men with prostate cancer catch a more accurate diagnosis sooner and minimize the need for unnecessary biopsies."


HDC plans to straight off begin presenting papers for publication and presentations at upcoming meetings as we initiate the marketing phase of commercialization. Because of the clinical trial success of this prostate malignant neoplastic disease test, the company plans to lead up a subject area utilizing piss samples to potentially enlarge the indication of this new prostate gland cancer test to be used as a screening tool, which could significantly expand the current market opportunity to include all men at risk for prostate cancer.

About Health Discovery Corporation


Savannah-based Health Discovery Corporation (OTCBB: HDVY) is uniquely positioned in the force field of rule recognition engineering. Through the application of its patent protected engineering science, HDC is a leader in SVM-based molecular symptomatic and prodigy test evolution in genomics and proteomics, as well as, digital image analysis in pathology and radiology. The Company's SVM and FGM radiation pattern recognition tools have significant application potential difference in other sizable commercial markets such as oil exploration, fiscal markets, Internet search and spam, native land security, and other areas where analysis of large volumes of complex information is requisite.


This news release contains "forward-looking statements" within the meaning of Section 27a of the Securities Acts of 1933 and Section 21E of the Securities Exchange Act of 1934. Although the management team of HDC believes that the expectations reflected in such forward-looking statements are reasonable, they can fall in no assurance that such expectations will prove correct.

Health Discovery Corporation


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Monday, 18 August 2008

Mp3 music: Wicked Lester






Wicked Lester
   

Artist: Wicked Lester: mp3 download


   Genre(s): 

Other

   







Wicked Lester's discography:


The Original Wicked Lester Session
   

 The Original Wicked Lester Session

   Year: 1972   

Tracks: 9






Although the band Wicked Lester never issued an official recording during their brief tenure together, the grouping would serve as a stepping stone for both Gene Simmons and Paul Stanley, both of whom later went on to discrepancy 1 of the '70s biggest punishing rock outfits, Kiss. Simmons and Stanley met in the late '60s through a mutual friend, Steve Coronel, barely it wasn't until Wicked Lester was formed in the early '70s that they reached whatever arcdegree of success. In add-on to Simmons (bass and vocals) and Stanley (guitar and vocals), the group likewise in the first place featured Coronel (cut guitar), Tony Zarella (drums), and Brooke Ostrander (keyboards), as the quint received a transcription contract from Columbia afterwards only playing a handful of gigs in the New York area.


Only the take came with one stipulation, that Coronel be replaced with a more complete participant. The request was granted (regular though Simmons and Coronel had been longtime friends), as some other guitar player, Ron Leejack, signed on. The newly instated lineup recorded an album's charles Frederick Worth of tracks at Jimi Hendrix's illustrious Electric Lady Studios in 1971, just the songs were the nail opposite of the orbit anthem/heavy metallic element that Kiss would after specialise in -- Wicked Lester was more a family to the chart-topping soft john Rock of the day (Rod Stewart, etc.), as their sound was an dental amalgam of several styles, something that Simmons and Stanley didn't feel very comfy with. Not glad with how the record album came out or the band's musical focus, the founding duet promptly announced their divergence from Wicked Lester, and the accomplished record album was shelved.


When Simmons and Stanley hit the magnanimous time with Kiss in the mid to late '70s, the unreleased Wicked Lester album gained major interest group among Kiss fans -- particularly later on a pair off of Wicked Lester songs, "She" and "Love Her All I Can," were re-cut by Kiss themselves for their 1975 Dressed to Kill album (some other early Kiss song, "Goin' Blind," was credited to both Simmons and Coronel, just appears to have been written either earlier or after Wicked Lester). The unreleased Wicked Lester album (and its art) was bought by Kiss' label, Casablanca, in 1977 so that Columbia wouldn't hard cash in on Kiss' success by releasing the aborted track record (which besides included pictures of Simmons and Stanley without make-up), only bootleg copies of the record album finally began making the rounds in fan circles. 2001 saw the appearance of the number 1 officially released Wicked Lester tracks ("Observe Me Waiting," as well as the said "She" and "Sexual love Her All I Can") on Kiss' self-titled, five-disc box mark.






Friday, 8 August 2008

Joss Stone playing homely wife in "Tudors"

LOS ANGELES (Hollywood Reporter) - In her first major acting use, British soul singer Joss Stone will play Henry VIII's one-quarter wife, Anne of Cleves, in Showtime's drama "The Tudors."





The gig will likely be a brief one, as Anne was married to Henry (Jonathan Rhys Meyers) for around six months.





A daughter of a German nobleman, Anne was betrothed to Henry in a marriage accord between the Cleves Court and the king's chancellor after Henry was shown a portrait of her.





Upon Anne's comer in England, Henry was disappointed in her looks and before long found a legal way to have the married couple annulled.





According to Showtime, the upcoming time of year of the racy imperial drama will follow the king as he weds Jane Seymour (Anita Briem) and then Anne of Cleves.





Stone, who explode onto the music picture in 2003 and has had threesome gold albums in the U.S., has been looking to bilk over into acting. In 2006, she had a role in the fantasy feature "Eragon." She is working on a new album.





/Hollywood Reporter









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